| Type of Biological Sample |
Components / Analytes |
Examination Technique |
Examination Procedure |
Status |
| Molecular Genetics |
| - Somatic Genes Mutation Anlaysis -50 Gene panel: ABL1, AKT1, ALK, APC, ATM, BRAF, CDH1, CDKN2A, CSF1R, CTNNB1, EGFR, ERBB2, ERBB4, EZH2, FBXW7, FGFR1, FGFR2, FGFR3, FLT3, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK2, JAK3, KDR, KIT, KRAS, MET, MLH1, MPL, NOTCH1, NPM1, NRAS, PDGFRA, PIK3CA, PTEN, PTPN11, RB1, RET, SMAD4, SMARCB1, SMO, SRC, STK11, TP53, VHL
| - Next Generation Sequencing. DNA Extraction, Library Preparation, Data QC, Variant analysis and annotations
| SOP #07 | Active
|
| - Herditiary Cancer Panel Genes (113) ACD, AIP, AKT1, APC, ATM, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1 ,CASR, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, CEBPA, CHEK2, CTRC, DDB2, DICER1, DIS3L2, EPCAM, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, FAM175A, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FH, FLCN, GALNT12, GATA2, GPC3, GREM1, HOXB13, KIF1B, KIT, LZTR1, MAX, MEN1, MET, MITF, MLH1, MRE11, MSH2, MSH3, MSH6, MUTYH, NBN, NF1, NF2, NSD1, NTLH1, PALB2, PDGFRA, PHOX2B, PIK3CA, PMS2, POLD1, POLE, POT1, PRKAR1A, PTCH1, PTEN, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RB1, RECQL4, RET, RHBDF2, RINT1, RUNX1, SDHA, SDHAF2, SDHB, SDHC, SDHD, SLX4, SMAD4, SMARCA4, SMARCB1, SMARCE1, SPINK1, SPRED1, STK11, SUFU, TERF2IP, TERT, TMEM127, TP53, TSC1, TSC2, VHL, WT1, XPA, XPC, XRCC2.
| SOP #08 | Active
|
| - PIK3CA Mutations: E542K, E545K, E545Q, H1047R, H1047L
| - Real-Time PCR.DNA Extraction, Real Time PCR
| SOP #32 (CFX OPUS 96) | Active
|
- EGFR Mutations (8 mutations): T790M, L858R, L861Q, S768I, Exon 19 Deletions - detects 44 deletions, G719X - Detects G719A, G719S, G719D and G719C, Exon 20 Insertions - detects 2319-2320 insCAC and 2310-2311 insGGT, Exon 20 Insertions - detects 2307-2
| - Real-Time PCR, DNA Extraction, Real Time PCR -CFX Opus 96
| SOP #31 | Active
|
- KRAS Mutations (12 mutations): Exon 2: G12R, G12C, G12S, G12V, G12A, G12D, G13D; Exon 3: Q16R. Q61H, Q61L: Exon 4: Detects K117N(AAC), K117N(AAT), K117R, K117E; Exon 4: Detects A146T, A146P, A146V
| - Real-Time PCR, DNA Extraction, Real Time PCR
| SOP #33 | Active
|
- NRAS Mutations (10 mutations): Exon 2: G12D, G12S, G12C, G13R, G13V; Exon 3: Q61K, Q61L, Q61R, Q61H; Exon 4: A146T
| SOP #34 | Active
|
- BRCA Panel Genes (6 genes): • BRCA1, BRCA2, CHEK2, PALB2, RAD51C, TP53
| - Next Generation Sequencing. DNA Extraction, Library Preparation, Data QC, Variant analysis and annotations
| SOP #43 | Active
|
- cfDNA/Blood in Streck tube
| - cfDNA Breast Cancer Panel (27 genes): AKT1, APC, AR, BRCA1, BRCA2, CCND1, CDH1, EGFR, ERBB2, ESR1, FGFR1, FGFR2, GATA3, IGF1R, KIT, KRAS, MAP2K4, MAP3K1, MDM2, MYC, NF1, PIK3CA, PIK3R1, PTEN, RB1, TOP2A, TP53
| - Next Generation Sequencing. cfDNA Extraction, Library Preparation, Data QC, Variant analysis and annotations
| SOP #44 | Active
|
- cfDNA Lung Cancer panel (28 genes): AKT1, ALK, ARAF, ARID1A, BRAF, CBL, CDKN2A, EGFR, ERBB2, HRAS, KEAP1, KRAS, MAP2K1, MET, MTOR, NF1, NRAS, NTRK1, NTRK2, PIK3CA, PTEN, RB1, RIT1, ROS1, SETD2, STK11, TP53, U2AF1
| SOP #44 | Active
|
- cfDNA Colorectal Cancer panel (15 genes): APC, ATM, BRAF, EGFR, ERBB2, FBXW7, KRAS, MET, NRAS, PDGFRA, PIK3CA, PTEN, SMAD4, TCF7L2, TP53
| SOP #44 | Active
|
